As a broad-spectrum antibacterial agent, the development trend of polyhexanide hydrochloride (PHMB) industry is improving

​​ ​​Polyhexamethylene biguanide hydrochloride (PHMB), also known as polyhexamethylene biguanide hydrochloride, has a molecular formula of C18H41ClN10 and is a chemical substance. PHMB appears as a colorless and transparent liquid with no special odor and is easily soluble in low molecular alcohol and water. PHMB contains highly active and bactericidal ingredients. As a broad-spectrum antibacterial agent, it is widely used in public environments, medical devices, food processing, textiles, home furnishings, agriculture and other fields.

The preparation method of PHMB is relatively simple. According to different raw materials, it can be divided into three types: 1,6-biscyanoguanidine method, sodium dicyandiamide method and dicyandiamide method. The 1,6-dicyanoguanide method refers to using 1,6-dicyanoguanide and hexamethylenediamine hydrochloride as the main raw materials, dissolving them in organic solvents under high temperature conditions, then adding catalysts, and making them through self-polycondensation reaction. Got PHMB. The 1,6-biscyanoguanidine method has the advantages of low production cost, high yield of finished products, and no pollution, and is suitable for industrial production.

The main raw materials of PHMB include hexamethylenediamine, 1,6-biscyanoguanidine, sodium dicyandiamide and dicyandiamide, among which hexamethylenediamine accounts for the main production cost. Restricted by factors such as insufficient supply of raw materials and high technical barriers, my country’s hexamethylenediamine production capacity was unable to meet market demand in the early days, and its reliance on imports was high. In recent years, driven by national policy support and technological innovation, my country’s hexamethylenediamine production capacity has expanded rapidly, reaching 480,000 tons in 2022. As the localization process of hexamethylenediamine continues to accelerate, the development trend of my country’s PHMB industry will continue to improve.

my country’s PHMB market is dominated by small and medium-sized enterprises, with low industry concentration and relatively scattered market competition. The main PHMB manufacturers in my country include Beijing Sangpu Biochemical Technology Co., Ltd., Hunan Lijie Biological Group Co., Ltd., Haining Zhonglian New Material Technology Co., Ltd., Wuhan Xindadi Environmental Protection Materials Co., Ltd., and Jiangsu Dafeng Yuelong Chemical Co., Ltd. wait.

As a broad-spectrum antibacterial agent, PHMB can eliminate Gram-negative bacteria, Gram-positive bacteria, yeasts and fungi, etc., and is widely used in many fields, including public environment, medical devices, food processing, textiles, home furnishings, and agriculture. wait. As consumers’ health concepts continue to increase, the market demand for sterilization and disinfection products is becoming increasingly strong, bringing broad development space to the PHMB industry. According to the “2023-2028 China Polyhexanide Hydrochloride (PHMB) Industry Market In-depth Research and Development Prospects Forecast Report released by the Industrial Research Center ” shows that my country’s PHMB market size will reach 1.94 billion yuan in 2022, a year-on-year increase of 7.9%.

Industry analysts said that the preparation process of PHMB is simple, its application prospects are broad, and the industry development trend continues to improve. As the localization process of raw materials continues to accelerate, my country’s PHMB production capacity will continue to increase. PHMB has a broad antibacterial spectrum, and with the rapid development of downstream industries, its market size will further expand. In terms of market competition, there are many PHMB manufacturers in my country and market competition is relatively scattered. As the industrial structure continues to be optimized, its industry concentration will increase.