Acetamide Acetamide

acetamide structural formula

Structural formula

Business number 01BD
Molecular formula C2H5NO
Molecular weight 59.07
label

Acetamide,

ammonium acetate,

Acetic acid amide,

Ethanamide,

Acetimidic acid,

Solubilizers,

Stabilizer for plasticizers,

antacids,

Wetting agents for the paper industry,

Nitrogen-containing compound solvent

Numbering system

CAS number:60-35-5

MDL number:MFCD00008023

EINECS number:200-473-5

RTECS number:AB4025000

BRN number:1071207

PubChem number:24849056

Physical property data

1. Properties: colorless hexagonal crystal. The pure product is odorless, but usually has a rat odor.

2. Boiling point (ºC, 101.3kPa): 221.15

3. Melting point (ºC): 81

4. Relative density (g/mL, 91.1 /4ºC): 0.9892

5. Relative density (g/mL,111.8/4ºC): 0.9711

6. Relative density (d204) : 1.159

7. Refractive index (80ºC): 1.4270

8. Refractive index (110ºC): 1.4158

9. Refractive index (130ºC): 1.4079

10. Viscosity (mPa·s, 91.1ºC): 2.182

11. Viscosity (mPa·s, 111.8ºC): 1.46

12. Viscosity (mPa·s, 131.7ºC): 1.056

13. Flash point (ºC, closed): >104

14. Fire point (ºC): 445

15. Heat of evaporation (KJ/mol, b.p.): 56.1

16. Heat of fusion (KJ/mol, 80ºC): 15.717

17. Heat of formation (KJ/mol): -320.7

18. Heat of combustion (KJ/mol, 25ºC, liquid): 1199.5

19. Specific heat capacity (KJ/(kg·K) , 80~150ºC, constant pressure): 2.81

20. Conductivity (S/m, 83.2ºC): 8.8×10-7

21 . Conductivity (S/m, 100ºC): 4.3×10-7

22. Freezing point (ºC): 80

23. Solubility: Soluble in liquid ammonia, aliphatic amines, water, alcohol, pyridine, chloroform, glycerin, hot benzene, methyl ethyl ketone, butanol, benzyl alcohol, cyclohexanone, isoamyl alcohol, etc., slightly soluble in benzene, insoluble in ether. Can dissolve most inorganic salts well.

Toxicological data

Low toxicity, oral LD50 in rats is0929/201009290927294698.gif” jquery1285723246906=”434″ alt=”” />

The generated ammonium acetate is heated and distilled (distilled above 190℃ and simultaneously Collect the product).
3. In the 1500L reaction jacketed tank,
Put 300kg of ethyl acetate and 500kg of ammonia water, stir at 25~27°C for 2~3h, leave it for 20h, and take the reaction solution. If stratification occurs, continue the reaction until there is no stratification.

After the reaction is completed, it is evaporated to 1/2 of the original volume under normal pressure, filtered, and the clear filtrate is concentrated under reduced pressure until slightly mixed, and cooled Crystallize, centrifuge and spin dry. If the CH3COO content is unqualified, soak it in ethanol for 0.5h, centrifuge and dry, and the finished product is ready.

Purpose

1. Molten acetamide is an excellent solvent for a variety of organic and inorganic substances. It can be used as a solubilizer when some substances with low water solubility are dissolved in water, such as solvents and solubilizers for dyes in the fiber industry. It is also widely used as a stabilizer for plasticizers, an antacid in the cosmetics industry, a wetting agent in the paper industry, and as a solvent in the synthesis of antibiotics such as chloramphenicol.

2.Used as analytical reagents, solvents, stabilizers, and plasticizers. It can also be used in organic synthesis, pharmaceutical industry, and dye preparation.

3. Also used to make hygroscopic agents, lubricants, etc.

This article is from the Internet, does not represent the position of Toluene diisocyanate reproduced please specify the source.https://www.chemicalchem.com/archives/23156

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