Acetamidozole 2-Acetamido-5-nitrothiazole

Structural formula

Business number	03T1
Molecular formula	C5H5N3O3S
Molecular weight	187.18
label	2-acetamido-5-nitrothiazole, 2-acetamido-5-nitrothiazole, 5-Nitro-2-acetilaminotiazolo, aromatic compounds

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:140-40-9

MDL number:MFCD00022438

EINECS number:205-414-7

RTECS number:XJ1570000

BRN number:None

PubChem ID:None

Physical property data

1. Physical property data

1.Characteristics: white crystalline powder, slightly odorous, almost tasteless

2.Melting point (℃): 264～266℃(decomposes ).

3.Solubility: in sodium hydroxide(potassium)lye and ammonia Moderately soluble, soluble in ethanol, slightly soluble in chloroform, slightly soluble in ether, almost insoluble in water

Toxicological data

2. Toxicological data:

1, Acute toxicity: Rat abdominal cavity LD50: >200 mg/kg;

Rat orally LD50 ：>400 mg/kg;

Rat subcutaneous LD: >3200 mg/kg;

Orally administered to mice LD50 ：200 mg/kg;

Mouse abdominal cavity LD50: >300 mg/kg;

Mouse subcutaneous LD: >3200 mg/kg.

Ecological data

3. Ecological data:

1, other harmful effects: This substance may be harmful to the environment, special attention should be paid to water bodies.

Molecular structure data

5. Molecular property data:

1. Molar refractive index:43.54

2. Molar volume (m³/ mol):117.0

3. Isotonic specific volume (90.2K): 343.8

4. Surface tension (dyne/cm): 74.4

5. Polarizability（10^-24cm³):17.26

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 1

3. Number of hydrogen bond acceptors: 5

4. Number of rotatable chemical bonds: 1

5. Number of tautomers: 5

6. Topological molecule polar surface area 116

7. Number of heavy atoms: 12

8. Surface charge: 0

9. Complexity: 205

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Stable under normal temperature and pressure.

Storage method

Stored sealed in a dry and cool place.

Synthesis method

By2-Aminothiazole is used as raw material.

Purpose

3. Isotonic specific volume (90.2K):343.8

4. Surface tension (dyne/cm): 74.4

5. Polarizability（10^-24cm³):17.26

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 1

3. Number of hydrogen bond acceptors: 5

4. Number of rotatable chemical bonds: 1

5. Number of tautomers: 5

6. Topological molecule polar surface area 116

7. Number of heavy atoms: 12

8. Surface charge: 0

9. Complexity: 205

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Stable under normal temperature and pressure.

Storage method

Stored sealed in a dry and cool place.

Synthesis method

By2-Aminothiazole is used as raw material.

Purpose

It is suitable for oral treatment of trichomoniasis, and can also be used for the treatment of amoebic and intestinal bacterial infections.

tyle=”FONT-SIZE: 10pt; COLOR: #333333; FONT-FAMILY: 宋体; mso-ascii-font-family: ‘Times New Roman’; mso-hansi-font-family: ‘Times New Roman'”>Applicable It is used for the oral treatment of trichomoniasis and can also be used to treat amoebic and intestinal bacterial infections.