Piperazine Citrate

Structural formula

Business number	03WE
Molecular formula	C24H46N6O14
Molecular weight	642.65
label	piperazine citrate, tri-Piperazine dicitrate

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:144-29-6

MDL number:MFCD00038961

EINECS number:205-622-8

RTECS number:TL3485000

BRN number:None

PubChem number:24870338

Physical property data

1. Physical property data

1. Characteristics: White crystalline powder or translucent crystalline particles.

2. Solubility:Easily soluble in water, very slightly soluble in methanol, insoluble in ethanol, ether, chloroform and benzene.

3. Boiling point (ºC,normal pressure): 182-187 ºC (decomposition)

Toxicological data

2. Toxicological data:

1, acute toxicity: oral administration to rats LD50 : 11200 mg/kg;

Small Rat oral LD50: 8500 mg/kg;

Small Mouse abdominal cavity LD50: 3548 mg/kg;

Small Mouse intravenous LDLo: 100 mg/kg;

Rabbit Intravenous LDLo: 175 mg/kg.

Ecological data

3. Ecological data:

Other harmful Effect: This substance may be harmful to the environment, and special attention should be paid to water bodies.

Molecular structure data

None

Compute chemical data

4. Calculated chemical data:

1. Hydrogen Bonding Number of donors: 6

2. Hydrogen Bonding Number of receptors: 9

3. Rotatable Number of chemical bonds: 5

4. Topological molecules Polar surface area (TPSA）：156

5. Heavy atoms Quantity: 19

6. Surface charge ：0

7. Complexity ：254

8. Number of isotope atoms: 0

9. Determine the number of atomic stereocenters:0

10. Uncertain number of atomic stereocenters:0

11. Determine the number of stereocenters of chemical bonds:0

12. Uncertain number of chemical bond stereocenters:0

13. Number of covalent bond units: 2

Properties and stability

Stable under normal temperature and pressure. SPAN>

Storage method

Save in a dry and cool place.

Synthesis method

Dissolve piperazine hexahydrate in distilled water, add activated carbon in 50-60℃Decolorize for half an hour and filter. Add citrate to the filtrate and add citric acid to 88-90 -family: 宋体”>℃Stir 1.5 hours. Cool to 35℃, add ethanol, cool and crystallize, filter, and dry to obtain the finished product.

Purpose

1.Anthelmintics, used for pinworm and roundworm infections.

2. Used as an anthelmintic

AMILY: 宋体; mso-bidi-font-family: 宋体”>℃Stir 1.5 hours. Cool to 35℃, add ethanol, cool and crystallize , filtered and dried to obtain the finished product.

Purpose

1.Anthelmintics, used for pinworm and roundworm infections.

2. Used as an anthelmintic