Andrographolide has high medicinal value and the extraction method is currently the main production process.

Andrographolide is the main active ingredient of the traditional Chinese medicine Andrographis paniculata. Under normal conditions, it mainly appears as white rectangular crystals with an extremely bitter taste. Andrographolide has the effects of clearing away heat and detoxifying, antibacterial and anti-inflammatory, protecting the liver and promoting choleretic effects. It is mainly used clinically to treat diseases such as pneumonia and upper respiratory tract infections in children. It has high medicinal value and is widely used in medicine, health products, cosmetics and other fields.

The main raw material of andrographolide is Andrographis paniculata. Andrographis paniculata is a traditional Chinese medicinal material in my country. It is bitter in taste and cold in nature. It has the effects of clearing heat, detoxifying, reducing inflammation and reducing swelling. It has high medicinal value. It is now widely planted in my country as a crop with both economic and medicinal value. Andrographis paniculata likes an environment with high temperature, humidity and sufficient sunlight. The southeastern coastal areas such as Guangdong and Fujian are the main producing areas of Andrographis paniculata in my country. Andrographolide content is one of the important indicators for evaluating the quality of Andrographis paniculata medicinal materials. In recent years, the quality of Andrographis paniculata in my country has declined due to factors such as over-harvesting, low variety purity, and delayed breeding of superior varieties, which may have a negative impact on the quality of andrographolide.

According to the “2023-2028 China Andrographolide Industry Market In-depth Research and Development Prospects Forecast Report released by the Industrial Research Center, At present, Andrographolide is mainly produced through extraction method. The extraction method mainly uses Andrographis paniculata stems and leaves as raw materials. After cold soaking in 95% ethanol, pure andrographolide is obtained through various processes such as reflux, decolorization, cooling, standing, filtration, crystallization, and purification. The extraction method has the advantages of high product purity and simple operation, but the production process is long, has many steps, consumes a large amount of ethanol, and has high production costs. The academic community is studying liquid phase catalytic hydrogenation and biosynthesis methods. It is expected that with more in-depth research in the future, the production process of andrographolide will usher in changes.

A variety of products with andrographolide as the main ingredient have appeared on the market, such as andrographolide tablets, andrographolide dropping pills, andrographolide facial masks, etc. Among them, injections made with andrographolide as the active ingredient are important products, including Chuanhuning injection, Yanhuning injection, Lianbizhi injection, etc.

Andrographolide belongs to the field of traditional Chinese medicinal materials. In recent years, the state has paid great attention to and supported the development of the traditional Chinese medicine industry, and has issued a series of relevant policies such as “Several Policies and Measures on Accelerating the Development of Traditional Chinese Medicine Characteristics” and “Action Plan for the High-Quality Development of the Pharmaceutical Industry (2023-2025)” 》etc. to promote the development of the Chinese herbal medicine industry, encourage the upgrading of the Chinese herbal medicine industry, optimize the industry structure, and strengthen the construction of Chinese herbal medicine brands. Industry analysts said that the introduction of these policies will further promote the structural adjustment and technology upgrade of my country’s andrographolide industry , high-quality development in the direction of policy guidance. In addition, the state also vigorously promotes traditional Chinese medicine culture to deepen residents’ acceptance and awareness of traditional Chinese medicine culture. It is expected that as residents’ acceptance and awareness of traditional Chinese medicine culture continue to increase, the market demand for andrographolide will continue to expand. .