Adenine nucleoside Adenosine

Structural formula

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:58-61-7

MDL number:MFCD00005752

EINECS number:200-389-9

RTECS number:AU7175000

BRN number:93029

PubChem number:24277685

Physical property data

1. Properties: White crystalline powder. Odorless. Sensitive to light and air.

2. Density (g/mL, 25/4℃): Undetermined

3. Relative vapor density (g/mL, air=1): Undetermined

4. Melting point (ºC): 234-235

5. Boiling point (ºC, normal pressure): Undetermined

6. Boiling point (ºC, 5.2kPa): Undetermined

7. Refractive index: Undetermined

8. Flash point (ºC): Undetermined

9. Specific rotation (º): [ -61.7°(C=0.706, water); -58.2°(C=0.658, water).

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa, 25ºC): Undetermined

12. Saturation Vapor pressure (kPa, 60ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Log value of oil-water (octanol/water) partition coefficient: Undetermined

17. Explosion upper limit (% ,V/V): Undetermined

18. Lower explosion limit (%,V/V): Undetermined

19. Solubility: Easily soluble in water, more soluble when hot , the solubility increases significantly in the presence of impurities, and it is almost insoluble in ethanol and ether.

Toxicological data

1. Acute toxicity: Intravenous TDLo in women: 240ug/kg; Intravenous TDLo in men: 143ug/kg/I; Intravenous TDLo in men: 50ug/kg/1M-I; Intravenous TDLo in women: 360ug/kg/1H-I; Intravenous TDLo in men: : 257ug/kg; male intravenous TDLo: 171ug/kg; male intravenous TDLo: 257ug/kg/1D-I; mouse menstrual��LD50: >20mg/kg; Mouse abdominal LD50: 500mg/kg

2. Mutagenicity: Phage inhibition capacityTEST system: Bacteria – Escherichia coli: 1mg/L; Mutation test system – not other specifiedTEST systems: Human cells – not otherwise specified: 100umol/L; genetic analysis: mouse peritoneal cavity: 178mg/kg; DNA damageTEST system: mammal – species not lymphocytes: 60mmol/L;

Ecological data

None

Molecular structure data

1. Molar refractive index: 59.95

2. Molar volume (cm³/mol): 128.1

3. Isotonic specific volume (90.2K ): 412.8

4. Surface tension (dyne/cm): 107.6

5. Polarizability (10^-24cm³): 23.76

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 4

3. Number of hydrogen bond acceptors: 8

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: 3

6. Topological molecule polar surface area 140

7. Number of heavy atoms: 19

8. Surface charge: 0

9. Complexity: 335

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 4

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

1. Avoid inhaling the dust of this product and avoid contact with eyes and skin.

Storage method

Seal with argon and store in a dry and dark place at 4°C.

Synthesis method

None

Purpose

1. Antiarrhythmic drugs can convert paroxysmal supraventricular tachycardia into sinus rhythm. For supraventricular arrhythmias related to the atrioventricular region.

2.Treatment of angina pectoris, myocardial infarction, coronary insufficiency, Arteriosclerosis, essential hypertension, cerebrovascular disorders, stroke sequelae, progressive muscle atrophy, etc.

3. Biochemical research.