Adenosine-5′-monophosphate Adenosine-5′-monophosphate

Structural formula

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:61-19-8

MDL number:MFCD00149360

EINECS number:200-500-0

RTECS number:AU7480500

BRN number:5205540

PubChem ID:None

Physical property data

1. Properties: white crystal. Easy to absorb moisture. Sensitive to light.

2. Density (g/mL, 25/4℃): Undetermined

3. Relative vapor density (g/mL, air=1): Undetermined

4. Melting point (ºC): 183-188

5. Boiling point (ºC, normal pressure): Undetermined

6. Boiling point (ºC, 5.2kPa): Undetermined

7. Refractive index: Undetermined

8. Flash point (ºC): Undetermined

9. Specific rotation (º, c= 2. In 2% sodium hydroxide solution): -47.5

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa, 25ºC) : Undetermined

12. Saturated vapor pressure (kPa, 60ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14 . Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Log value of oil-water (octanol/water) partition coefficient: Undetermined

17. Explosion upper limit (%, V/V): Undetermined

18. Explosion lower limit (%, V/V): Undetermined

19. Solubility : Easily soluble in hot water and acetone, slightly soluble in ethanol, insoluble in ether.

Toxicological data

1. Acute toxicity: Mouse abdominal LC50: 4mg/kg 2. Reproductive toxicity: Female rat abdominal TDLo: 2800mg/kg, 7-13 days after conception; Female mouse abdominal TCLo: 2800mg/kg, 7-13 days after conception 3. Mutagenicity: Mutation test system – not other specifiedTEST system: human cells – not otherwise specified: 100umol/L; DNA inhibitionTEST system: rodent – rat liver: 10mmol/L; Mutation test system – not other specifiedTEST system : rodentMaterial – Mouse Liver: 10mmol/L; Mutation Test System – Not Other SpecifiedTEST System: Rodent – Mouse Cells – Not Otherwise Specified: 50umol/L

Ecological data

None yet

Molecular structure data

1. Molar refractive index: 69.90

2. Molar volume (cm³/mol): 149.6

3. Isotonic specific volume (90.2K): 515.5

4. Surface tension (dyne/cm): 140.9

5. Polarizability (10^-24cm³): 27.71

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 5

3. Number of hydrogen bond acceptors: 11

4. Number of rotatable chemical bonds: 4

5. Number of tautomers: 3

6. Topological molecule polar surface area 186

7. Number of heavy atoms: 23

8. Surface charge: 0

9. Complexity: 481

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 4

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Adenylate is one of the four main single nucleotides that make up the ribonucleic acid of animal cells. It is an energy transfer substance in the body, but it is more stable than adenotriphosphate (ATP). It has significant peripheral vasodilation and antihypertensive effects.

Storage method

Seal and store in a dry place below 0℃ and away from light.

Synthesis method

None yet

Purpose

1. Biochemical research.

2.Clinically used for disseminated sclerosis, porphyria, pruritus, liver disease, and varicose ulcer complications. Compound eye drops mainly composed of adenylate can be used for eye fatigue, central retinitis, corneal surface diseases such as pannus and herpes.