Toluene diisocyanate manufacturer Knowledge How is dichloroacetic acid made? Properties and brief preparation method of dichloroacetic acid

How is dichloroacetic acid made? Properties and brief preparation method of dichloroacetic acid

[Alias]Dichloroacetic acid.

[Molecular Formula]C2H2Cl2O2

[Structural Formula]Cl2CHCOOH

二 Chloroacetic acid

[Properties]Colorless, highly corrosive liquid with pungent odor. Relative density 1.564 (20℃), boiling point 193-194℃. Two different crystals can be generated, with melting points of 9.7°C and -4°C respectively. Easily soluble in water, and also in solvents such as alcohols, ketones, hydrocarbons, and chlorinated hydrocarbons. It is a stronger acid than chloroacetic acid, and both Cl atoms can be replaced. It reacts with aromatic hydrocarbons to form diaryl acetic acid, reacts with phenol to form diphenoxyacetic acid, and can produce cross-linking when reacting with cellulose. Its acidic vapor is irritating to mucous membranes.

[Use]Used as an organic synthesis and pharmaceutical intermediate for the manufacture of methyl dichloroacetate, allantoin and cationic dyes wait. Dichloroacetic acid has bactericidal and disinfectant activities and can be used as a disinfectant in medicine. It also has the ability to inhibit a variety of staphylococci and is also used as a keratinolytic and astringent agent.

[Brief preparation method]

① Acetic acid is produced by chlorination under the action of iodine catalyst. It can also be obtained by chlorination reaction of chloroacetic acid mother liquor under sulfur catalysis.

②Produced by the reaction of trichloroacetaldehyde hydrate and potassium cyanide in the laboratory.

[Safety and Protection]Dichloroacetic acid is a second-level organic acid corrosive substance, hazard regulation number: 94004. Packed in 20kg plastic drum or 70kg large mouth plastic drum. Store in a cool, ventilated and dry place. Be careful not to be exposed to heat or impact during storage and transportation. If your skin comes into contact, rinse immediately with plenty of water.

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