sulfaacetyl

Sulfonamide Acetyl Structural Formula

Structural formula

Business number 03WL
Molecular formula C8H10N2O3S
Molecular weight 214.24
label

N-(4-aminobenzenesulfonyl)acetamide,

acesulfonamide sodium salt,

acesulfonamide,

N-(4-Aminobenzenesulfonyl)acetamide

Numbering system

CAS number:144-80-9

MDL number:MFCD00066501

EINECS number:205-640-6

RTECS number:AC8450000

BRN number:981718

PubChem number:24899803

Physical property data

1. Physical property data:


1. Character:White crystalline powder
-bidi-font-family: Tahoma”>2. Melting point (ºC): 182-184ºC
3. Solubility:Soluble in ethanol, slightly soluble in water or ether, almost insoluble in chloroform or benzene, soluble in dilute mineral acid or alkali hydroxide Solution.

Toxicological data

2. Toxicological data:


1, acute toxicity: rat intravenous LD50: 6600 mg/kg;


Mouse oral LD50: 16500 mg/kg;


Mouse abdominal cavity LD50: 606 mg/kg.


2. Reproductive toxicity: RatTDLo: 10 gm/kg

Ecological data

3. Ecological data:


Other harmful Effect: This substance may be harmful to the environment, and special attention should be paid to water bodies.

Molecular structure data


5. Molecular property data:


1. Molar refractive index:52.21


2. Molar volume (m3/mol):155.9


3. Isotonic specific volume (90.2K):424.7


4. Surface tension (dyne/cm):55.0


5. Polarizability(10-24cm3):20.69

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 2

3. Number of hydrogen bond acceptors: 4

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: 2

6. Topological molecule polar surface area 97.6

7. Number of heavy atoms: 14

8. Surface charge: 0

9. Complexity: 299

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Stable under normal temperature and pressure. 2. Moore Volume (m3/mol ): 155.9


3. Isotonic specific volume (90.2K):424.7


4. Surface tension (dyne/cm):55.0


5. Polarizability(10-24cm3):20.69

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 2

3. Number of hydrogen bond acceptors: 4

4. Number of rotatable chemical bonds: 2

5. Number of tautomers: 2

6. Topological molecule polar surface area 97.6

7. Number of heavy atoms: 14

8. Surface charge: 0

9. Complexity: 299

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

Stable under normal temperature and pressure.

Storage method

Save at 0-6ºC.

Synthesis method

Obtained by acidification of sodium sulfonamide acetate. Dissolve sodium sulfonamide acetate in water and use 5%Hydrochloric acid is adjusted to pH3.8-4 to precipitate sulfonamide acetyl. Filter, wash and dry to get the finished product.

Purpose

Medicine, used to treat conjunctivitis, trachoma and other eye infections.

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Storage method

Save at 0-6ºC.

Synthesis method

Obtained by acidification of sodium sulfonamide acetate. Dissolve sodium sulfonamide acetate in water and use 5%Hydrochloric acid is adjusted to pH3.8-4 to precipitate sulfonamide acetyl. Filter, wash and dry to get the finished product.

Purpose

Medicine, used to treat conjunctivitis, trachoma and other eye infections.

This article is from the Internet, does not represent the position of Toluene diisocyanate reproduced please specify the source.https://www.chemicalchem.com/archives/27705

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