The market demand for 3-methyl-2-nitrobenzoic acid is increasing, and the development and optimization of the synthesis process are crucial

3-Methyl-2-nitrobenzoic acid appears as white to light beige crystalline powder and is easily soluble in methanol and dimethyl sulfoxide. 3-Methyl-2-nitrobenzoic acid has many active sites in its molecular structure. As a fine chemical intermediate, it is widely used in pesticides, medicine, bioengineering, dyes, organic synthesis and other fields.

The upstream products of 3-methyl-2-nitrobenzoic acid include m-toluic acid, 3-methyl-2-nitrobenzoyl chloride, 2-amino-3-methylbenzoic acid, and m-toluonitrile etc., the downstream products involve 2-aminoisophthalic acid, 2-amino-3-methylbenzoic acid, o-toluidine, methyl 3-methyl-2-nitrobenzoate, etc. 3-Methyl-2-nitrobenzoic acid is one of the key intermediates of chlorantraniliprole. In recent years, with the expansion of chlorantraniliprole production capacity, the 3-methyl-2-nitrobenzoic acid market has welcomed the There is a broader space for development.

Chlorantraniliprole is one of the world’s mainstream pesticides. It was launched by DuPont of the United States. In 2017, DuPont of the United States transferred the information and property rights of chlorantraniliprole to FMC. In addition, chlorantraniliprole manufacturers also include Bayer of Germany. , India’s Best Agrolife, etc. In 2022, global sales of chlorantraniliprole will be around US$2.45 billion. Due to the expiration of patented compounds, the number of enterprises in my country continues to increase, and the production capacity of chlorantraniliprole is expanding rapidly. Since 2020, the total declared production capacity of chlorantraniliprole has reached about 100,000 tons.

In order to expand competitive advantages and reduce procurement costs, chlorantraniliprole companies are supporting upstream main raw materials and actively create advantages in the entire industry chain. With the expansion of chlorantraniliprole production capacity, the scale of the 3-methyl-2-nitrobenzoic acid industry will further expand.

According to the “2023-2028 China 3-methyl-2-nitrobenzoic acid industry market in-depth research and development prospect forecast report released by the Industrial Research Center> shows that my country’s research and development of 3-methyl-2-nitrobenzoic acid started in the 1980s. At present, relevant domestic suppliers include Nantong Runfeng Petrochemical, Shanghai Chuangsai Technology, and Jiuxin Biotechnology , Shanghai Jizhi Biochemical Technology, etc.

The synthesis process of 3-methyl-2-nitrobenzoic acid mostly involves nitration reaction, which has problems such as high risk, low product conversion rate, and difficulty in purification and separation. In order to realize the green, safe, low-cost, and cost-effective chlorantraniliprole industry, It is crucial to develop, develop and optimize the 3-methyl-2-nitrobenzoic acid synthesis process on a large scale. In 2023, the China Pesticide Industry Association issued a “Solicitation for Green Nitrification Technology of m-Toluic Acid” for scientific research institutions, technical communities, enterprises and other entities.

Industry analysts said that in recent years, with the expansion of application fields, the market demand for 3-methyl-2-nitrobenzoic acid has increased The continuous release and rapid expansion of chlorantraniliprole production capacity will also bring broader development space for the 3-methyl-2-nitrobenzoic acid market. In the future, as the synthesis process continues to be optimized, the 3-methyl-2-nitrobenzoic acid industry will continue to develop in the direction of environmental protection, efficiency, and greenness.