With the continued implementation of anti-antibiotic regulations in feed, the tributyrin industry is ushering in a period of development opportunities

Tributyrin is an organic compound with the chemical formula C15H26O6. It refers to a glyceride formed by the esterification of one molecule of glycerol and three molecules of butyric acid. It appears as a white, almost oily liquid, almost odorless, and is easily soluble in ethanol, Chloroform and ether are extremely insoluble in water.

The main production methods of tributyrin include esterification method, which refers to the method of using butyric acid and glycerin as raw materials, and under the action of acidic catalyst, through esterification reaction to generate tributyrin; transesterification method, refers to the method of using fatty acids A method in which lower alcohol esters and glycerin are used as raw materials, and tributyrin is generated through transesterification under the catalysis of lower sodium alcoholate or lower potassium alcoholate. Among them, the esterification method is currently the most widely used production method of tributyrin.

Tributyrin is mainly used in the feed industry as a feed additive. Tributyrin can pass through the animal’s stomach without being broken down. After entering the intestine, it begins to break down into butyric acid and glycerol, which are fully absorbed by the animal’s body and provide it with an energy source. Butyric acid is the main energy source for animal colon mucosal epithelial cells. It has the functions of promoting the development of animal intestinal cells, maintaining intestinal barrier function, reducing intestinal inflammatory response, and inhibiting harmful bacteria.

In the current context of the ongoing implementation of domestic feed-side “antibiotic ban” regulations, in order to make up for the vacancy in pharmaceutical growth-promoting additives after the withdrawal of antibiotics from the feed market, tributyrin has become a hot product, and the market penetration rate has continued to increase. According to data from the China Feed Industry Association, the total output value of the national feed industry in 2022 will be 1.31685 billion yuan, an increase of 7.6% over the previous year. In recent years, against the background of the rapid development of the domestic feed industry, the market demand for tributyrin has continued to increase, and the industry has ushered in a period of development opportunities. According to the“China Tributyrin Market Monitoring and Future Development Prospects Research Report 2023-2027” released by the Industrial Research Center It shows that the domestic tributyrin market size will reach 1.31 billion yuan in 2022.

At present, the number of tributyrin manufacturers in my country is relatively small, mainly including Lutianhua Group, Hebei Jingu Renewable Resources Development, Shandong Huayu New Materials, Henan Bangji Biochemical Technology, Zhejiang Huineng Biotech, and Shandong Dezhou Shenniu Pharmaceutical. , Jiangsu Ruijia New Materials, Anhui Aidibei Biotechnology, Nanjing Newbond Biotechnology, etc. In the future, with the rapid development of the domestic feed industry, the number of companies entering the tributyrin market is expected to continue to increase, and the industry has huge room for growth.

Industry analysts said that tributyrin is an important type of feed additive that can be used in After entering the animal’s intestines, it is decomposed into butyric acid and glycerol, providing an energy source for the animal. In recent years, under the background of the continuous implementation of domestic feed “antibiotic ban” regulations, tributyrin has become a “star” additive to replace antibiotics. Its market penetration rate has been continuously improved, and the industry has broad prospects for development.