The market demand for parafluorobenzene continues to rise. my country is the world’s major producer and exporter.
Para-fluorobenzene, also known as p-bromofluorobenzene, is a chemical substance with the molecular formula C6H4BrF. It appears as a colorless and transparent liquid at room temperature and pressure. It is insoluble in water and soluble in organic solvents such as benzene, toluene, and ether. Parafluorobromobenzene is an important class of organic synthesis and pharmaceutical chemical intermediates with broad application prospects in the fields of medicine, pesticides and chemical industry.
Specifically, in the pharmaceutical field, p-fluorobromobenzene can be used in the synthesis of 5-bromo-2-fluorophenol, the intermediate of the antidepressant drug Tritonin, and in the production of the antifungal drug flusilazole. ; In the field of pesticides, p-fluorobenzene can be used in the synthesis of the new pyrazole amide acaricide pyridoxyfen; in the field of chemical industry, p-fluorobenzene can be used in the production of additives for coatings, plastics and adhesives, and can also be used for sterilization Synthesis scenario of flusilazole.
According to the “Research Report on Market Monitoring and Future Development Prospects of China’s Parafluorobenzene Industry from 2023 to 2027” released by the Industrial Research Center It shows that fungicides and acaricides are the main application scenarios of parafluorobenzene. Currently, under the background of rapid development of downstream application fields, domestic demand for parafluorobenzene is increasing. Taking acaricides as an example, its domestic market size will reach 820 million yuan in 2022, a year-on-year increase of 4.5%. As a result, my country’s market demand for parafluorobenzene has exceeded 50,000 tons in 2022.
There are currently two common production processes for p-fluorobenzene. One is to use fluorobenzene, pyridine, and bromine as raw materials to generate hydrogen bromide gas, which is then subjected to water absorption, heating, cooling, ether extraction, drying, fractionation, etc. The first step is the process of generating p-fluorobenzene; the second step is the process of using fluorobenzene and elemental bromine as reactants and performing a bromination reaction under the action of iron powder catalyst to generate p-fluorobenzene.
There are a large number of p-fluorobenzene companies in China. The main companies include Shandong Brothers Chemical, Wuhan Xinweiye Chemical, Zhejiang Yongtai Technology, Fuxin Boman Biotechnology, Yancheng Longsheng Chemical, Yancheng Shengda Chemical, Hubei Xinhongli Chemical, Nanjing Fusida Chemical, etc., but most of them are small and medium-sized enterprises, the industry concentration is low, and no leading enterprise has yet emerged. In recent years, with the gradual release of production capacity of local enterprises, my country has gradually become the world’s major producer and exporter of parafluorobenzene, with an annual production capacity of about 120,000 tons.
Industry analysts said that p-fluorobenzene is an important type of organic synthesis and fine chemical intermediates , playing an important role in medicine, pesticides, chemicals, daily chemicals and other fields. With the rapid development of downstream application fields, my country’s demand for fluorobenzene continues to increase, and the industry shows good development prospects. At the same time, against the background of the gradual upgrading of local enterprises’ production technology, my country’s production capacity of parafluorobromobenzene has continued to increase, and it has become a major producer and exporter in the world. The overall development trend of the industry is good.