Latest article
Preparation of 4-tert-octylresorcinol_Kain Industrial Additive
Overview[1] Chroman-2-one is a tyrosinase inhibitor suitable for lightening human skin or for the prevention and/or treatment of pigment defects such as hyperpigmentation, freckles, age spots, sun spo…
![Preparation method of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazacyclolan-2-one _Kain Industrial Additives](https://www.chemicalchem.com/wp-content/themes/iux/thumb.php?src=/images/169951536481914.jpg&w=300&h=193)
Preparation method of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazacyclolan-2-one _Kain Industrial Additives
Background and overview[1] Ezetimibe was jointly developed by Schering-Plough and Merck for the treatment of hyperlipidemia. It was approved by the US FDA for marketing in 2002 under the trade name Ze…
Preparation method of 2-hydroxy-3′-nitro-biphenyl-3-carboxylic acid_Kain Industrial Additive
Background and overview[1] Eltrombopag (trade name: Promacta) was developed by the British company GlaxoSmithKline. It was approved by the FDA for marketing in the United States in November 2008. It i…
Main applications of 3-aminodibenzofuran_Kain Industrial Additives
Background and Overview[1] 3-Aminodibenzofuran can be used as a pharmaceutical synthesis intermediate. Preparation[1] 1) Synthesis of 3-nitrodibenzofuran: Add 150ml trifluoroacetic acid to the reactio…
Main applications of 4,4’-biphenyldiphenol_Kain Industrial Additives
Background and overview[1] 4,4′-biphenyldiphenol is widely used in the chemical industry to prepare engineering composites, polyester, Modified monomers of polyurethane, polyphenylsulfone, epoxy resin…
Preparation method of 5-bromobenzofuran_Kain Industrial Additive
Background and overview[1] Benzofuran and its derivatives such as 5-bromobenzofuran are very important organic compounds with high biological activity and are widely present in the skeleton of many na…
N-[5-[4-[(1,1-dioxo-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-A]pyridine -2-yl]cyclopropanecarboxamide_Kain Industrial Additive
Background and overview[1] N-[5-[4-[(1,1-dioxo-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5- A]pyridin-2-yl]cyclopropanecarboxamide can be used as a pharmaceutical synthesis intermediate. Prepa…
Applications of poly(p-phenylene terephthalamide)_Kain Industrial Additives
Overview[1] Poly(p-phenylene terephthalamide) is an all-para-polyaramid formed by the condensation polymerization of p-phenylenediamine and terephthaloyl chloride. It has a rigid chain structure. It c…
Preparation method of 3-(4-bromophenyl)piperidin-2-one_Kain Industrial Additive
Background and overview[1] 3-(4-Bromophenyl)piperidin-2-one can be used as a pharmaceutical synthesis intermediate. Preparation[1] 3-(4-Bromophenyl)piperidin-2-one is prepared as follows: To ethyl 2-(…
Preparation method of deuterated acetophenone_Kain Industrial Additive
Overview[1] Deuterated acetophenone is a deuterated reagent that can be prepared from benzene-d6 in two steps. Preparation method[1] Step 1: Preparation of acetophenone-2′,3′,4′,5…
