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Applications of 3-phenylbut-2-enoic acid_Kain Industrial Additives

Overview[1][2] 3-Phenylbut-2-enoic acid can be prepared in one step from triethyl phosphonoacetate and phenylacetaldehyde, and can be used to synthesize 2-position disubstituted indolin-3-one compound…

Preparation of 4-(1H-benzimidazol-2-yl)phenol_Kain Industrial Additive

Overview[1] 4-(1H-Benzimidazole-2-yl)phenol is benzimidazole and its derivatives. Benzimidazole and its derivatives are a class of heterocyclic compounds with potential anti-cancer and bactericidal bi…

3-Maleimidobenzoic acid succinimidyl ester_Kain Industrial Additive

3-Maleimidobenzoic acid succinimidyl ester_Kain Industrial Additive

Background and overview[1] 3-Maleimidobenzoic acid succinimidyl ester is a widely used intermediate in pharmaceuticals, agricultural chemicals, dyes and polymer compounds. Yoshio Igarashi et al. repor…

Main applications of pyridine 4-toluenesulfonate_Kain Industrial Additives

Main applications of pyridine 4-toluenesulfonate_Kain Industrial Additives

Background and overview[1] Pyridine 4-methylbenzenesulfonate can be used as a pharmaceutical synthesis intermediate. Apply[1-3] Pyridine 4-methylbenzenesulfonate can be used as a pharmaceutical synthe…

Main applications of phenyfluorenone_Kain Industrial Additives

Main applications of phenyfluorenone_Kain Industrial Additives

Background and overview[1] With the improvement of scientific and technological level in recent years, acidic chromogens have been widely used in chemical analysis. In chemical detection, acidic chrom…

Application of 4-cyanomethyl-2,3,5,6-tetrafluorobenzonitrile_Kain Industrial Additive

Overview[1][2] 4-Cyanomethyl-2,3,5,6-tetrafluorobenzonitrile is a photochemical intermediate that can be prepared from hexafluorobenzonitrile in one step and can be used to synthesize luminescent mate…

Preparation of 4-tert-octylresorcinol_Kain Industrial Additive

Overview[1] Chroman-2-one is a tyrosinase inhibitor suitable for lightening human skin or for the prevention and/or treatment of pigment defects such as hyperpigmentation, freckles, age spots, sun spo…

Preparation method of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazacyclolan-2-one  _Kain Industrial Additives

Preparation method of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazacyclolan-2-one _Kain Industrial Additives

Background and overview[1] Ezetimibe was jointly developed by Schering-Plough and Merck for the treatment of hyperlipidemia. It was approved by the US FDA for marketing in 2002 under the trade name Ze…

Preparation method of 2-hydroxy-3′-nitro-biphenyl-3-carboxylic acid_Kain Industrial Additive

Background and overview[1] Eltrombopag (trade name: Promacta) was developed by the British company GlaxoSmithKline. It was approved by the FDA for marketing in the United States in November 2008. It i…

Main applications of 3-aminodibenzofuran_Kain Industrial Additives

Background and Overview[1] 3-Aminodibenzofuran can be used as a pharmaceutical synthesis intermediate. Preparation[1] 1) Synthesis of 3-nitrodibenzofuran: Add 150ml trifluoroacetic acid to the reactio…

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