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Preparation of 2-fluoro-4-iodoaniline_Kain Industrial Additive

Background and Overview[1] 2-Fluoro-4-iodoaniline is one of the most important intermediates in the dye industry. In the dye industry, it can be used to manufacture acid ink blue G, acid medium BS, ac…

Preparation of 3-bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one_Kain Industrial Additive

Background and Overview[1] 3-Bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one is an intermediate in the synthesis of benazepril hydrochloride. Benazepril hydrochloride is a first-line antihypertensive …

Preparation of benzene sulfonyl chloride_Kain Industrial Additive

Background and Overview[1] Benzenesulfonyl chloride is a white flake crystal with a melting point of 69-71°C. It is an important organic synthesis drug intermediate and is mainly used in the synthesis…

Preparation of m-methoxypropiophenone_Kain Industrial Additive

Background and Overview[1] Me-methoxypropiophenone is a key intermediate used in the production of the drug tapentadol. Tapentadol is a novel oral analgesic drug that acts on the central nervous syste…

Application of (R)-2-(aminoethyl)-4-chlorophenol_Kain Industrial Additive

Background and overview[1][2] (R)-2-(Aminoethyl)-4-chlorophenol is a chiral organic intermediate, which can be prepared by reductive amination of 2-hydroxy-5-chloroacetophenone and then chiral separat…

Preparation of α-methylbenzonitrile_Kain Industrial Additive

Background and overview[1] α-Methylbenzonitrile, also called 2-phenylpropionitrile, can be used to synthesize 2-phenylpropionic acid, which is widely used in the synthesis of medicines, spices and pes…

Preparation and application of 6,7-dihydro-4(5H)-benzofuranone_Kain Industrial Additive

Background and overview[1] 6,7-Dihydro-4(5H)-benzofuranone is an important pharmaceutical intermediate. It can be prepared by the reaction of 1,3-cyclohexanedione and chloroacetaldehyde aqueous soluti…

Preparation of 2-(2-methoxy-4-niphenyl)-3-(4-niphenyl)-5-(2,4-disulfobenzene)-2H-tetrazole monosodium salt_Kay Yin industrial additives

Background and overview[1] 2-(2-Methoxy-4-niphenyl)-3-(4-niphenyl)-5-(2,4-disulfobenzene)-2H-tetrazole monosodium salt, WST-8, referred to as WST-8, is a main component in the cell activity detection …

(2S-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H)-one Preparation_Kain Industrial Additives

Background and overview[1] (2S-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5H) -Ketone is a key intermediate in the synthesis of diltiazem. The current route to synthesize…

Preparation and application of [1,1′-bis(diphenylphosphine)ferrocene]palladium dichloride dichloromethane complex_Kain Industrial Additive

Background and overview[1] [1,1′-bis(diphenylphosphine)ferrocene]palladium dichloride dichloromethane complex (Pd(dppf)Cl2·CH2 Cl2) is a bimetallic solvent complex formed by Pd(II) and dppf, which is …

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