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Preparation method of etizolam intermediate_Kain Industrial Additive
Background and overview[1] Etizolam is a benzodiazepine anti-anxiety drug. Its anti-anxiety effect is 3 to 5 times stronger than that of diazepam, but its effect is not exactly the same as that of dia…
Preparation of 2-benzyl-5-chloro-1,2,3,4-tetrahydro-[2,6]naphthyridine_Kain Industrial Additive
Background[1][2] 2-Benzyl-5-chloro-1,2,3,4-tetrahydro-[2,6]naphthyridine can be used as a pharmaceutical synthesis intermediate and an organic synthesis intermediate, mainly used in experiments Labora…
Preparation of 4-[4-[(5S)-5-(aminomethyl)-2-carbonyl-3-zolidinyl]phenyl]-3-morpholinone_Kain Industrial Additive
Background and overview[1][2] 4-[4-[(5S)-5-(aminomethyl)-2-carbonyl-3-zolidinyl]phenyl]-3-morpholinone is an intermediate for the preparation of rivaroxaban, Rivaroxaban is a new type of anticoagulant…
Preparation of methyl 4-methanesulfonylbenzoate_Kain Industrial Additive
Background and overview[1][2] Aryl sulfones have special chemical properties and biological activities, and their structures can be found in many drugs. As an important class of organic compounds, the…
Clinical application of bifonazole_Kain Industrial Additives
Bifonazole Bifonazole cream is a milky white or slightly yellow cream. Each gram contains 10 mg of bifonazole as the main ingredient. The excipients are stearic acid, glyceryl monostearate, liquid par…
Application of benzophenone_Kain Industrial Additives
Background and overview[1][2] Biphenyl acetophenone is an intermediate for the synthesis of biphenylacetic acid. Biphenylacetic acid is a good non-steroidal anti-inflammatory drug and an effective met…
Main applications of D-phenylalanine_Kain Industrial Additives
Background and overview[1] The scientific name of phenylalanine is α-amino-β-phenylpropionic acid. It is a kind of α-amino acid. It has L type, D type and racemic DL type. The L type is one of the ess…
Preparation and application of 2-cyano-5-fluorobenzoic acid_Kain Industrial Additive
Overview[1] 2-Cyano-5-fluorobenzoic acid is an organic intermediate that can be prepared from 2-bromo-5-fluorobenzoic acid methyl ester in two steps. Preparation[1] Step a: Heat a mixture of 2-bromo-5…
Application of 2-bromo-6-iodobenzoic acid_Kain Industrial Additive
Overview[1] 2-Bromo-6-iodobenzoic acid is a carboxylic acid substance that can be used as a pharmaceutical synthesis intermediate. Preparation[1] 2-Bromo-6-iodobenzoic acid is prepared as follows: 2-b…
Application of 3,4-dichlorobenzeneglyoxal hydrate_Kain Industrial Additive
Overview[1] 3,4-Dichlorophenylglyoxal hydrate is the monohydrate of 3,4-dichlorophenylglyoxal. 3,4-Dichlorophenylglyoxal is an organic intermediate and has been reported to be used in the preparation …
