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Application of 4-aldehyde benzocyclobutene_Kain Industrial Additive
Background and overview[1] 4-Aldehyde benzocyclobutene is an organic intermediate that can be prepared from 4-bromobenzocyclobutene. Preparation[1] Add 50 mL of anhydrous tetrahydrofuran (THF), Mg chi…
Application of 4-tert-butyl-2,6-dinitrophenol_Kain Industrial Additive
Background and overview[1] 4-tert-butyl-2,6-dinitrophenol is an organic intermediate that can be prepared by nitration of 4-tert-butylphenol. Preparation[1] Dissolve 4-tert-butylphenol (25g, 170mmol) …
Application of 4-nitro-3,5-dimethylbenzoic acid_Kain Industrial Additive
Background and overview[1] 4-Nitro-3,5-dimethylbenzoic acid is an organic intermediate that can be obtained by oxidation of 1,3,5-2-nitrobenzene. Preparation[1] To an acetic acid solution in which chr…
Preparation and application of 5-phenyl o-anisidine_Kain Industrial Additives
Background and overview[1] 5-Phenyl-o-anisidine, also called 3-amino-4-methoxybiphenyl, can be prepared from p-hydroxybiphenyl through a three-step reaction. Preparation[1] Preparation of compound bip…
Application of 5-fluorobenzothiazole_Kain Industrial Additive
Background and overview[1] 5-Fluorobenzothiazole is an organic intermediate that can be prepared from 5-fluoro-2-aminothiophenol as a starting material. Preparation[1] 5-fluorobenzothiazole:1H NMR (40…
Preparation and application of phenyl trifluoromethanesulfonate_Kain Industrial Additive
Background and overview[1] Phenyl trifluoromethanesulfonate, also called phenyl triflate, can be used in organic synthesis and can be obtained by acylation of phenol. Preparation[1-3] Phenyl triflate:…
Preparation method of tritylvalsartan_Kain Industrial Additive
Background and overview[1] Tritylvalsartan is the precursor of valsartan and can be used to prepare valsartan. Valsartan is a widely used antihypertensive drug in clinical practice. It has the advanta…
Preparation of 2,5-diphenylfuran_Kain Industrial Additive
Background and overview[1] Heterocyclic compounds, especially natural products containing furan and thiophene structures, mostly have good biological activity. Therefore, how to synthesize heterocycli…
Preparation of 2,5-dimethoxyphenylethylamine hydrochloride_Kain Industrial Additive
Background and overview[1] 2,5-Dimethoxyphenylethylamine is the main raw material for the synthesis of 5-hydroxytryptamine (5-HT) compounds. Its main synthesis method consists of 2,5-dimethoxybenzalde…
Preparation of 2-amino-4-(3-bromophenyl)thiazole_Kain Industrial Additive
Background and overview[1] Heterocyclic compounds are widely found in nature, accounting for about half of organic compounds. 2-Aminothiazole ring derivatives are a very important member of heterocycl…
