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Preparation and application of [1,1′-bis(diphenylphosphine)ferrocene]palladium dichloride dichloromethane complex_Kain Industrial Additive
Background and overview[1] [1,1′-bis(diphenylphosphine)ferrocene]palladium dichloride dichloromethane complex (Pd(dppf)Cl2·CH2 Cl2) is a bimetallic solvent complex formed by Pd(II) and dppf, which is …
Preparation method and application of m-chloroperoxybenzoic acid_Kain Industrial Additive
Background and overview[1-2] Metachloroperoxybenzoic acid is a commonly used oxidizing agent in organic synthesis. It can oxidize alkenes, carbonyl compounds, nitrogen-, sulfur-, phosphorus-, selenium…
2-[2-[2-Chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indole-2-ylidene)ethylidene]-1-cyclohexane Preparation of en-1-yl]vinyl]-1,3,3-trimethyl-3H-indole 4-methylbenzenesulfonate_Kain Industrial Additive
Background and overview[1] 2-[2-[2-Chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indole-2-ylidene)ethylene]-1 -Cyclohexen-1-yl]vinyl]-1,3,3-trimethyl-3H-indole 4-methylbenzenesulfonate is a cyanine dye an…
Preparation of N-[4-(sulfonamide)phenyl]acrylamide_Kain Industrial Additive
Background and overview[1-2] N-[4-(Sulfonamide)phenyl]acrylamide (ASPAA) monomer can be homopolymerized or copolymerized with other monomers to form pharmacologically active polymers that are water-so…
Preparation of 4-hydroxy-3-methoxy-2-nitrobenzaldehyde_Kain Industrial Additive
Background and overview[1] 4-Hydroxy-3-methoxy-2-nitrobenzaldehyde can be used as a pharmaceutical intermediate, which can be prepared through a three-step reaction using vanillin as the starting mate…
Preparation of 5,6-diphenyl-2-hydroxypyrazine_Kain Industrial Additive
Background and overview[1] 5,6-Diphenyl-2-hydroxypyrazine is a pharmaceutical intermediate that can be prepared in one step from benzoyl and aminoacetamide hydrochloride. There are reports in the lite…
Preparation of (3R,4S)-3-hydroxy-4-phenyl-2-azetidinone_Kain Industrial Additive
Background and overview[1] (3R,4S)-3-Hydroxy-4-phenyl-2-azetidinone, referred to as (-)β-lactam, is a very potential chiral drug intermediate. There are two isomers, namely (3R, 4S) configuration and …
Preparation of 2,4-diphenyl-oxazacyclo-5-acid_Kain Industrial Additive
Background and overview[1] 2,4-Diphenyl-oxazacyclo-5-acid is a pharmaceutical intermediate that can be prepared in two steps from (2R,3S)-3-phenylisoserine and trimethyl orthobenzoate. get. It has bee…
Preparation of (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-3,5-oxazolidinedicarboxylic acid 3-tert-butyl ester_Kain Industrial Additive
Background and overview[1] (4S,5R)-2-(4-Methoxyphenyl)-4-phenyl-3,5-oxazolidinedicarboxylic acid 3-tert-butyl ester is a pharmaceutical intermediate, which can be made from ( 2′R,3′S)-phenylisoserine …
Preparation and application of p-toluenesulfonic acid tsoh_Kain Industrial Additive
Background and Overview P-Toluenesulfonic acid (tsoh) was first prepared by Jaworsky in 1865 by sulfonating toluene with sulfuric acid. In 1869, Engelllardt and others discovered that ortho and meta i…
