Latest article
Preparation and application of 1,3,5-tris(4-iodophenyl)benzene_Kain Industrial Additive
Background and overview[1] 1,3,5-Tris(4-iodophenyl)benzene is an organic intermediate that can be prepared in two steps from 1,3,5-tribromobenzene and p-trimethylsilylbenzeneboronic acid. It has been …
Preparation of 5-methanoyl-2-methyl-benzonitrile_Kain Industrial Additive
Background and overview[1-2] 5-Methanoyl-2-methyl-benzonitrile is an organic intermediate. According to literature reports, it can be synthesized from 3-(dimethylammonium)acrylonitrile and (E,E)-2,4-h…
Preparation and application of phenol-D6_Kain Industrial Additive
Background and overview[1-3] Phenol-D6 is deuterated phenol, which can be prepared from phenol and heavy water in one step. Phenol-D6 can be used as an internal standard or for the preparation of stab…
Preparation of 4-cyclohexyl-3-trifluoromethylbenzoic acid_Kain Industrial Additive
Background and overview[1] 4-Cyclohexyl-3-trifluoromethylbenzoic acid is an organic intermediate that can be used to prepare the compound N-(4-cyclohexyl-3-trifluoromethyl-benzyloxy)-ethylimine acid e…
Preparation of 2,2′-bis(trifluoromethyl)diaminobiphenyl_Kain Industrial Additive
Background and overview[1] 2,2′-bis(trifluoromethyl)diaminobiphenyl is also called 2,2′-bis(trifluoromethyl)-4,4’diaminobiphenyl. 2,2′-bis(trifluoromethyl)-4,4’diaminobip…
Preparation and application of 2-nitro-5-chloroaniline_Kain Industrial Additive
Background and overview[1] 2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It is currently used in fenbendazole, an upgraded product of the veterinary drug alb…
Preparation and application of 3,5-dihydroxypentylbenzene_Kain Industrial Additive
Background and overview[1-2] 3,5-Dihydroxypentylbenzene is an important pharmaceutical intermediate, which was first obtained by degrading lichenic acid (also known as D-usroleic acid and amylyliscoli…
Preparation and application of 5-amino-2-nitrotrifluorotoluene_Kain Industrial Additive
Background and overview[1-2] 5-Amino-2-nitrotrifluorotoluene is an organic intermediate that can be prepared from m-chlorotrifluorotoluene in two steps. There are literature reports that it can be use…
Preparation and application of 5-chloro-2-hydroxyacetophenone_Kain Industrial Additive
Background and overview[1] 5-Chloro-2-hydroxyacetophenone can be nitrated to prepare 5-chloro-2-hydroxy-3-nitroacetophenone. 5-Chloro-2-hydroxy-3-nitroacetophenone is a key drug intermediate for the s…
Preparation of N-(3-methylphenyl)-4-(4-pyridine)-2-thiazolamine_Kain Industrial Additive
Background and overview[1] N-(3-methylphenyl)-4-(4-pyridine)-2-thiazolamine belongs to the 4-pyridyl-2-anilinothiazole (PAT) class of compounds and is effective against renal cell carcinoma (RCC). Cel…
